IL-6 boosts synaptogenesis STAT!
Abstract
Maternal infection during pregnancy increases the offspring's risk of developing neurodevelopmental disorders. While IL-6 is involved, the mechanism by which IL-6 and other cytokines affect developing neural circuits is unknown. In this issue of Immunity, Mirabella et al. (2021) show that the pro-inflammatory cytokine IL-6 specifically increases synaptogenesis in immature excitatory neurons through downstream neuronal STAT3-dependent...
Paper Details
Title
IL-6 boosts synaptogenesis STAT!
Published Date
Nov 1, 2021
Journal
Volume
54
Issue
11
Pages
2444 - 2446
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Notes
History