mRNA expression of specific HER ligands and their association with clinical outcome in patients with metastatic breast cancer treated with trastuzumab

Vassiliki Rapti; Evangelia Moirogiorgou; Georgia-Angeliki Koliou; Kyriaki Papadopoulou; I. Binas; George Pentheroudakis; Dimitrios Bafaloukos; Mattheos Bobos; Kyriakos Chatzopoulos; Sofia Chrisafi; Vassiliki Kotoula; George Fountzilas

doi:https://doi.org/10.3892/ol.2021.13141

doi.org/10.3892/ol.2021.13141

mRNA expression of specific HER ligands and their association with clinical outcome in patients with metastatic breast cancer treated with trastuzumab

Vassiliki Rapti

1

,

Evangelia Moirogiorgou

1

,

..., George Fountzilas

56

Oncology Letters2.90

Volume: 23, Issue: 1

Published: Nov 17, 2021

Abstract

Prognostic and predictive biomarkers are being studied for the diagnosis and treatment of breast cancer. The present study retrospectively assessed the mRNA expression of HER family receptor ligands and of other potential prognostic biomarkers and their association with time to progression (TTP), survival and clinicopathological characteristics in patients with metastatic breast cancer (MBC) treated with trastuzumab. A total of 145 tumour tissue...

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Paper Details

Title

mRNA expression of specific HER ligands and their association with clinical outcome in patients with metastatic breast cancer treated with trastuzumab

DOI

doi.org/10.3892/ol.2021.13141

Published Date

Nov 17, 2021

Journal

Oncology Letters

Volume

23

Issue

1

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