Abstract 9486: Effect of Statin Therapy on Cognitive Decline and Incident Dementia in Older Adults

Background: The neurocognitive effect of statins in older adults remains uncertain. Objectives: To investigate the associations of statin use with cognitive decline and incident dementia among older adults. Methods: This analysis included 18,846 participants (aged ≥65 years) from a randomized trial of aspirin (ASPirin in Reducing Events in the Elderly, ASPREE). At baseline, participants had no experience of a CVD event, major physical...