Development, Physical–Chemical Characterization, and Molecular Docking Simulations of Ursolic Acid–Sodium Alginate Complexes

The aim of this study was to fabricate ursolic acid (UA)-sodium alginate (SA) complexes to improve the dissolution rate and antioxidant abilities. The antioxidant activity was evaluated by the DPPH (1,1-diphenyl-2-trinitrophenylhydrazine) assay and the pyrogallol auto-oxidation method. For the optimal composition ratio of UA:SA (1:5, w/w), the cumulative release of UA was about 101.22 ± 1.50% for 180 min. Powder X-ray diffractometry (PXRD),...