Reduction of clinical safety margins in proton therapy enabled by the clinical implementation of dual-energy CT for direct stopping-power prediction
Abstract
To quantifiy the range uncertainty in proton treatment planning using dual-energy computed tomography (DECT) for a direct stopping-power prediction (DirectSPR) algorithm and its clinical implementation.To assess the overall uncertainty in stopping-power ratio (SPR) prediction of a DirectSPR implementation calibrated for different patient geometries, the influencing factors were categorized in imaging, modeling as well as others. The respective...
Paper Details
Title
Reduction of clinical safety margins in proton therapy enabled by the clinical implementation of dual-energy CT for direct stopping-power prediction
Published Date
Jan 1, 2022
Journal
Volume
166
Pages
71 - 78
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