Quantitative Hydrogen/Deuterium Exchange Mass Spectrometry

Volume: 32, Issue: 12, Pages: 2711 - 2727
Published: Nov 8, 2021
Abstract
This Account describes considerations for the data generation, data analysis, and data interpretation of a hydrogen/deuterium exchange-mass spectrometry (HDX-MS) experiment to have a quantitative argument. Although HDX-MS has gained its popularity as a biophysical tool, the argument from its data often remains qualitative. To generate HDX-MS data that are more suitable for a quantitative argument, the sequence coverage and sequence resolution...
Paper Details
Title
Quantitative Hydrogen/Deuterium Exchange Mass Spectrometry
Published Date
Nov 8, 2021
Volume
32
Issue
12
Pages
2711 - 2727
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