Use of Diagnostic Ions for the Detection of Fentanyl Analogs in Human Matrices by LC–QTOF

Volume: 32, Issue: 12, Pages: 2852 - 2859
Published: Nov 18, 2021
Abstract
To combat the ongoing opioid epidemic, our laboratory has developed and evaluated an approach to detect fentanyl analogs in urine and plasma by screening LC-QTOF MS/MS spectra for ions that are diagnostic of the core fentanyl structure. MS/MS data from a training set of 142 fentanyl analogs were used to select the four product ions and six neutral losses that together provided the most complete coverage (97.2%) of the training set compounds....
Paper Details
Title
Use of Diagnostic Ions for the Detection of Fentanyl Analogs in Human Matrices by LC–QTOF
Published Date
Nov 18, 2021
Volume
32
Issue
12
Pages
2852 - 2859
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