Black dots: High-yield traction force microscopy reveals structural factors contributing to platelet forces
Abstract
Measuring the traction forces produced by cells provides insight into their behavior and physiological function. Here, we developed a technique (dubbed 'black dots') that microcontact prints a fluorescent micropattern onto a flexible substrate to measure cellular traction forces without constraining cell shape or needing to detach the cells. To demonstrate our technique, we assessed human platelets, which can generate a large range of forces...
Paper Details
Title
Black dots: High-yield traction force microscopy reveals structural factors contributing to platelet forces
Published Date
Jun 1, 2023
Journal
Volume
163
Pages
302 - 311
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Notes
History