Subacute AMD3100 Treatment Is Not Efficient in Neonatal Hypoxic-Ischemic Rats
Abstract
Despite the advances in treating neonatal hypoxic-ischemic encephalopathy (HIE) with induced hypothermia, the rates of severe disability are still high among survivors. Preclinical studies have indicated that cell therapies with hematopoietic stem/progenitor cells could improve neurological outcomes in HIE. In this study, we investigated whether the administration of AMD3100, a CXCR4 antagonist that mobilizes hematopoietic stem/progenitor cells...
Paper Details
Title
Subacute AMD3100 Treatment Is Not Efficient in Neonatal Hypoxic-Ischemic Rats
Published Date
Feb 1, 2022
Journal
Volume
53
Issue
2
Pages
586 - 594
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