Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes

Volume: 71, Issue: 2, Pages: 285 - 297
Published: Nov 9, 2021
Abstract
Red blood cells (RBC) act as mediators of vascular injury in type 2 diabetes mellitus (T2DM). miR-210 plays a protective role in cardiovascular homeostasis and is decreased in whole blood of T2DM mice. We hypothesized that downregulation of RBC miR-210 induces endothelial dysfunction in T2DM. RBC were coincubated with arteries and endothelial cells ex vivo and transfused in vivo to identify the role of miR-210 and its target protein tyrosine...
Paper Details
Title
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes
Published Date
Nov 9, 2021
Journal
Volume
71
Issue
2
Pages
285 - 297
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