A Priori Knowledge of Maximum Achievable Organ at Risk Sparing: Impact on Organ Doses and Patient Reported Outcomes

IMRT planning is challenging, at least in part, due to the essentially-infinite number of possibilities, and since the planner is never sure that they have gotten "the best", or at least "nearly the best" achievable plan. We prospectively assessed the impact of providing IMRT planners with a priori knowledge of the maximum achievable dose sparing for organs at risk (OARs) for patients on both dosimetric and clinical endpoints. We hypothesized...