Synthesis, crystal structure of a novel tetranuclear Cu (II) complex and its application in GSH-triggered generation of reactive oxygen species for chemodynamic therapy

Volume: 25, Issue: 12, Pages: 101372
Published: Dec 1, 2021
Abstract
null null A novel tetranuclear copper complex (TCC) has been successfully synthesized and characterized using high resolution mass spectrometry (HRMS), Fourier transform infrared spectroscopy (FTIR) and X-ray single crystal diffraction technique. TCC was capable of triggering by Glutathione (GSH) to produce Cu (Ⅰ), then the resulted Cu (Ⅰ) further converted the overexpression of endogenous H2O2 into •OH, a highly cytotoxic reactive oxygen...
Paper Details
Title
Synthesis, crystal structure of a novel tetranuclear Cu (II) complex and its application in GSH-triggered generation of reactive oxygen species for chemodynamic therapy
Published Date
Dec 1, 2021
Volume
25
Issue
12
Pages
101372
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