Stereodivergent Synthesis of BothZ- andE-Alkenes by Photoinduced, Ni-Catalyzed Enantioselective C(sp³)–H Alkenylation

The enantio- and stereoselective synthesis of stereodefined alkenes, especially the functionalized Z-isomer with an allylic stereogenic center, remains a great challenge. We herein report an enantioselective benzylic C(sp3)–H alkenylation of simple alkylarenes with vinyl bromides via photoinduced nickel catalysis, which allows for the stereodivergent synthesis of both enantioenriched Z- and E-alkenes bearing aryl-substituted, allylic tertiary...