Picornaviral 2C proteins: A unique ATPase family critical in virus replication.

Volume: 49, Pages: 235 - 264
Published: Jan 1, 2021
Abstract
null null The 2C proteins of Picornaviridae are unique members of AAA + protein family. Although picornavirus 2C shares many conserved motifs with Super Family 3 DNA helicases, duplex unwinding activity of many 2C proteins remains undetected, and high-resolution structures of 2C hexamers are unavailable. All characterized 2C proteins exhibit ATPase activity, but the purpose of ATP hydrolysis is not fully understood. 2C is highly conserved among...
Paper Details
Title
Picornaviral 2C proteins: A unique ATPase family critical in virus replication.
Published Date
Jan 1, 2021
Volume
49
Pages
235 - 264
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