miR ‐146b Protects the Perinatal Brain against Microglia‐Induced Hypomyelination
Abstract
Objectives In the premature newborn, perinatal inflammation mediated by microglia contributes significantly to neurodevelopmental injuries including white matter injury (WMI). Brain inflammation alters development through neuroinflammatory processes mediated by activation of homeostatic microglia toward a pro‐inflammatory and neurotoxic phenotype. Investigating immune regulators of microglial activation is crucial to find effective strategies to...
Paper Details
Title
Published Date
Nov 26, 2021
Journal
Volume
91
Issue
1
Pages
48 - 65
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