Cronkhite–Canada syndrome: An investigation in clinical features and pathogenesis

Cronkhite-Canada syndrome (CCS) is a rare nonhereditary polyposis syndrome and its pathogenesis is poorly understood. This study aimed to investigate the clinical features and potential pathogenesis of CCS.Eight patients with CCS admitted to our hospital from January 2005 to November 2019 were thoroughly evaluated. Transcriptome profiling was performed on characterizing gastric polyp and normal mucosa from one CCS patient. Differentially...