Impact of co-administered stabilizers on the biopharmaceutical performance of regorafenib amorphous solid dispersions
Volume: 169, Pages: 189 - 199
Published: Dec 1, 2021
Abstract
Poor solubility of drug candidates is a well-known and thoroughly studied challenge in the development of oral dosage forms. One important approach to tackle this challenge is the formulation as an amorphous solid dispersion (ASD). To reach the desired biopharmaceutical improvement a high supersaturation has to be reached quickly and then be conserved long enough for absorption to take place. In the presented study, various formulations of...
Paper Details
Title
Impact of co-administered stabilizers on the biopharmaceutical performance of regorafenib amorphous solid dispersions
Published Date
Dec 1, 2021
Volume
169
Pages
189 - 199
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