HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Abstract
Maternal-fetal immune-tolerance occurs throughout the whole gestational trimester, thus a mother can accept a genetically distinct fetus without immunological aggressive behavior. HLA-G, one of the non-classical HLA class I molecules, is restricted-expression at extravillous trophoblast. It can concordantly interact with various kinds of receptors mounted on maternally immune cells residing in the uterus (e.g. CD4+ T cells, CD8+ T cells, natural...
Paper Details
Title
HLA-G: An Important Mediator of Maternal-Fetal Immune-Tolerance
Published Date
Oct 29, 2021
Journal
Volume
12
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