Clinical and virological characteristics of viral shedding in children with norovirus gastroenteritis

The correlation between the clinical manifestations and fecal viral load of norovirus (NoV) infection remains unknown.We established a SYBR® Green-based real-time quantitative reverse transcriptase polymerase chain reaction (qRT-PCR) method to quantify NoV and then sequenced its genomes from the feces of patients admitted at the Chang Gung Memorial Hospital from 2017 to 2018.NoV GII.4 Sydney (n = 21, 36.2%) and GII.P16-GII.2 (n = 19, 32.8%), the...