Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study

Volume: 76, Issue: 3, Pages: 536 - 548
Published: Mar 1, 2022
Abstract
•Reduced ALT, AST, GGT, FIB-4, and FibroTest scores were seen with OCA vs. placebo. •Reduced liver stiffness by VCTE was observed in OCA vs. placebo arms at Month 18. •NIT changes in OCA treatment arms were associated with shifts in fibrosis stage. •The antifibrotic effect of OCA might be measurable with commonly used NITs. Background & Aims Non-alcoholic steatohepatitis (NASH) is a chronic, progressive fibrotic liver disease that can lead to...
Paper Details
Title
Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study
Published Date
Mar 1, 2022
Volume
76
Issue
3
Pages
536 - 548
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