Harnessing microbial iron chelators to develop innovative therapeutic agents
Abstract
Bacterial infections involving multidrug-resistant Gram-negative bacteria have become critically involved in the current antibiotic crisis. This, together with the bacterial evolution ability, prioritizes the discovery of new antibiotics. Research on microbial iron acquisition pathways and metabolites, particularly siderophores, has highlighted hopeful aspects for the design of advanced antimicrobial approaches. Moreover, exploiting siderophores...
Paper Details
Title
Harnessing microbial iron chelators to develop innovative therapeutic agents
Published Date
Jul 1, 2022
Journal
Volume
39
Pages
89 - 101
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History