Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling
Abstract
Previous reports have proposed the importance of signalling and material exchange between cartilage and subchondral bone. However, the specific experimental evidence is still insufficient to support the effect of this interdependent relationship on mutual cell behaviours. In this study, we aimed to investigate cellular lipid metabolism in chondrocytes induced by osteoblasts.Osteoblast-induced chondrocytes were established in a Transwell chamber....
Paper Details
Title
Osteoblasts impair cholesterol synthesis in chondrocytes via Notch1 signalling
Published Date
Nov 2, 2021
Journal
Volume
54
Issue
12
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