Increased cGAS/STING signaling components in patients with Mooren’s ulcer

To explore the expression of cGAS/STING signaling components in Mooren's ulcer (MU).Samples were obtained from ten MU patients, and eight residual corneal-scleral rings of healthy donor corneas for controls. Human corneal epithelial cells (HCECs) were used to evaluate the effect of cGAS/STING signaling pathway. Immunohistochemistry (IHC) and Western blot were used to examine the expression of cGAS, STING, and phosphorylated interferon regulatory...