Mas-related G protein-coupled receptor D is involved in modulation of murine gastrointestinal motility.

New findings null What is the central question of this study? The physiological implication of MrgprD in gastrointestinal motility is unknown. The aim of this study is to assess the effects of MrgprD and its receptor agonists on murine gastrointestinal motility. What is the main finding and its importance? Mrgprd deficiency improves the mouse gastrointestinal motility in vivo but has no effects on the spontaneous contractions of murine...