Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders

Volume: 186, Issue: 6, Pages: 376 - 388
Published: Sep 1, 2021
Abstract
Common genetic variation appears to largely influence risk for neuropsychiatric disorders through effects on gene regulation. It is therefore possible to shed light on the biology of these conditions by testing for enrichment of associated genetic variation within regulatory genomic regions operating in specific tissues or cell types. Here, we have used the assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-Seq) to...
Paper Details
Title
Sites of active gene regulation in the prenatal frontal cortex and their role in neuropsychiatric disorders
Published Date
Sep 1, 2021
Volume
186
Issue
6
Pages
376 - 388
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