A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes

Volume: 135, Issue: 5
Published: Nov 2, 2021
Abstract
Hepatic lipid homeostasis depends on intracellular pathways that respire fatty acid in peroxisomes and mitochondria, and on systemic pathways that secrete fatty acid into the bloodstream, either free or condensed in very-low-density lipoprotein (VLDL) triglycerides. These systemic and intracellular pathways are interdependent, but it is unclear whether and how they integrate into a single cellular circuit. Here, we report that mouse liver...
Paper Details
Title
A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes
Published Date
Nov 2, 2021
Volume
135
Issue
5
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