OncomiRs miR-106a and miR-17 negatively regulate the nucleoside-derived drug transporter hCNT1

Volume: 78, Issue: 23, Pages: 7505 - 7518
Published: Oct 13, 2021
Abstract
High-affinity uptake of natural nucleosides as well as nucleoside derivatives used in anticancer therapies is mediated by human concentrative nucleoside transporters (hCNTs). hCNT1, the hCNT family member that specifically transports pyrimidines, is also a transceptor involved in tumor progression. In particular, oncogenesis appears to be associated with hCNT1 downregulation in some cancers, although the underlying mechanisms are largely...
Paper Details
Title
OncomiRs miR-106a and miR-17 negatively regulate the nucleoside-derived drug transporter hCNT1
Published Date
Oct 13, 2021
Volume
78
Issue
23
Pages
7505 - 7518
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