Establishment of substance P modified affinity chromatography for specific detection and enrichment of Mas-related G protein–coupled receptor X2
Abstract
Mas-related G protein-coupled receptor X2 (MrgX2) has been identified to be critical in drug-induced pseudo-allergic reactions and allergic diseases. Herein, an affinity high-performance liquid chromatography was established for the specific detection and enrichment of MrgX2. Substance P was used as an affinity ligand and immobilized on a glutaraldehyde-modified amino silica gel. The successful grafting of substance P was characterized by...
Paper Details
Title
Establishment of substance P modified affinity chromatography for specific detection and enrichment of Mas-related G protein–coupled receptor X2
Published Date
Dec 1, 2021
Journal
Volume
1659
Pages
462633 - 462633
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