A specialist antigen storage compartment in dendritic cells to sustain cross‐presentation

Dendritic cells (DCs) play a key role in inducing, shaping and maintaining adaptive immune responses. DCs act as professional antigen-presenting cells, uniquely able to prime the differentiation of naive T cells. DCs reside in all tissues of the body, collecting antigen for transport to the local draining lymph nodes and for presentation to a hugely diverse repertoire of T cells that recirculate between the blood and lymphoid organs. Crucially,...