Involvement of polymorphisms of complement lectin pathway serine proteases encoding genes in etiopathogenesis of ischemic stroke

Complement is a major part of innate immune system. The complement system is a proteolytic cascade, where serine proteases activate each other by limited proteolysis in a strictly ordered manner. Serine proteases are essential in both the initiation and the amplification of the cascade. The aim of current study was to reveal the possible involvement of complement lectin pathway mannan-binding lectin-associated serine proteases, MASP-1 and MASP-2...