Nuclear morphology in breast lesions: refining its assessment to improve diagnostic concordance

Although evaluation of nuclear morphology is important for the diagnosis and categorisation of breast lesions, the criteria used to assess nuclear atypia rely upon the subjective evaluation of several features that may result in inter- and intraobserver variation. This study aims to refine the definitions of cytonuclear features in various breast lesions.ImageJ was used to assess the nuclear morphological features including nuclear diameter,...