PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation

Volume: 37, Issue: 1, Pages: 109776 - 109776
Published: Oct 1, 2021
Abstract
PIWI proteins are known as mediators of transposon silencing in animal germlines but are also found in adult pluripotent stem cells of highly regenerative animals, where they are essential for regeneration. Study of the nuclear PIWI protein SMEDWI-2 in the planarian somatic stem cell system reveals an intricate interplay between transposons and cell differentiation in which a subset of transposons is inevitably activated during cell...
Paper Details
Title
PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
Published Date
Oct 1, 2021
Volume
37
Issue
1
Pages
109776 - 109776
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