Construction of CF3-Functionalized Fully Substituted Benzonitriles through Rauhut–Currier Reaction Initiated [3 + 3] Benzannulation
Volume: 86, Issue: 21, Pages: 14844 - 14854
Published: Oct 1, 2021
Abstract
Though numerous cyanation reactions have been developed for the synthesis of benzonitriles, the construction of valuable fully substituted benzonitriles is still a challenging task. Herein, we reported a tertiary amine-catalyzed [3 + 3]-benzannulation for the green synthesis of CF3-functionalized fully substituted benzonitriles. This strategy features exclusive chemoselectivity, high atom-economy, and good step-economy with environment-friendly...
Paper Details
Title
Construction of CF3-Functionalized Fully Substituted Benzonitriles through Rauhut–Currier Reaction Initiated [3 + 3] Benzannulation
Published Date
Oct 1, 2021
Volume
86
Issue
21
Pages
14844 - 14854
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