Seizure control does not predict hippocampal subfield volume change in children with focal drug-resistant epilepsy

Background and purpose Recurrent seizures have been reported to induce neuronal loss in the hippocampus. It is unclear whether seizure control influences hippocampal volume. The aims of this study were to determine if there was a change in total or subfield hippocampal volume over time in children with focal drug-resistant epilepsy, and whether seizure control influenced total or subfield hippocampal volumes. Methods Using FreeSurfer’s automated...