Endoscopic Management of Hamartomatous Polyposis Syndromes

To review the clinical diagnosis, recommended endoscopic surveillance, and endoscopic management of the hamartomatous polyposis syndromes (HPS) including (1) Peutz-Jeghers syndrome (PJS), (2) juvenile polyposis syndrome (JPS), and 3) PTEN hamartomatous syndromes (PHTS). Device-assisted enteroscopy (DAE) with polypectomy is now first-line treatment for small bowel polyps identified on surveillance with VCE or CT/MRI enterography. The efficacy and...