MiR-122 radiosensitize hepatocellular carcinoma cells by suppressing cyclin G1

Emerging evidence has shown that radiotherapy is an effective treatment for hepatocellular carcinoma (HCC), Micro(mi)RNAs are involved in regulating radiosensitivity in many cancers. MiR-122 accounts for approximately 70% of all cloned miRNAs in the liver, but there are few reports about whether it is involved in regulating of radiosensitivity in HCC cells.HCC cells (HepG2 and Huh7) overexpressing miR-122 were constructed by transfecting them...