Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma
Abstract
Hepatocellular carcinoma (HCC) is an aggressive human cancer with increasing incidence worldwide. Multiple efforts have been made to explore pharmaceutical therapies to treat HCC, such as targeted tyrosine kinase inhibitors, immune based therapies and combination of chemotherapy. However, limitations exist in current strategies including chemoresistance for instance. Tumor initiation and progression is driven by reprogramming of metabolism, in...
Paper Details
Title
Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma
Published Date
Feb 1, 2022
Journal
Volume
12
Issue
2
Pages
558 - 580
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Notes
History