Adult sucrase-isomaltase deficiency masquerading as IBS
Abstract
Recently in Gut, several publications reported an increased prevalence of hypomorphic (defective) sucrase-isomaltase ( SI ) gene variants in patients with irritable bowel syndrome (IBS),1 2 and the association with impaired cell-surface expression and reduced digestive function of the corresponding enzyme.3 In addition, hypomorphic SI carriers have shown reduced response compared with non-carriers in a low-FODMAP (fermentable oligo- di-...
Paper Details
Title
Adult sucrase-isomaltase deficiency masquerading as IBS
Published Date
Oct 6, 2021
Journal
Volume
71
Issue
6
Pages
1237 - 1238
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Notes
History