Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples

Volume: 55, Issue: 5, Pages: 553 - 568
Published: Oct 2, 2021
Abstract
Maintenance of whole-body ascorbate levels and distribution is mediated via sodium-dependent vitamin C transporters (SVCTs). The kidney is one of a few organs that express both SVCT1 and SVCT2. Recent evidence suggests that accumulation of ascorbate may be different in tumour compared to normal tissue, but data on SVCT levels in tumours is sparse.The role of the two SVCT isoforms in ascorbate uptake in renal cell carcinoma (RCC) was investigated...
Paper Details
Title
Limited Association Between Ascorbate Concentrations and Vitamin C Transporters in Renal Cell Carcinoma Cells and Clinical Samples
Published Date
Oct 2, 2021
Volume
55
Issue
5
Pages
553 - 568
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