Low prevalence of amyloid and tau pathology in drug‐resistant temporal lobe epilepsy
Abstract
Cognitive impairment is common in patients with chronic drug-resistant temporal lobe epilepsy (TLE). Hyperphosphorylated tau (pTau) and amyloid-β (Aβ) plaques, pathological hallmarks of Alzheimer disease, have been hypothesized to play a mechanistic role. We investigated Aβ plaques and pTau prevalence in TLE patients who underwent resective surgery and correlated their presence with preoperative psychometric test scores and clinical...
Paper Details
Title
Low prevalence of amyloid and tau pathology in drug‐resistant temporal lobe epilepsy
Published Date
Sep 30, 2021
Journal
Volume
62
Issue
12
Pages
3058 - 3067
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