Interpretation of cancer mutations using a multiscale map of protein systems
Abstract
Mapping protein interactions driving cancer Cancer is a genetic disease, and much cancer research is focused on identifying carcinogenic mutations and determining how they relate to disease progression. Three papers demonstrate how mutations are processed through networks of protein interactions to promote cancer (see the Perspective by Cheng and Jackson). Swaney et al . focus on head and neck cancer and identify cancer-enriched interactions,...
Paper Details
Title
Interpretation of cancer mutations using a multiscale map of protein systems
Published Date
Oct 1, 2021
Journal
Volume
374
Issue
6563
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