Retinal pigment epithelium 65 kDa protein (RPE65): An update
Abstract
Vertebrate vision critically depends on an 11-cis-retinoid renewal system known as the visual cycle. At the heart of this metabolic pathway is an enzyme known as retinal pigment epithelium 65 kDa protein (RPE65), which catalyzes an unusual, possibly biochemically unique, reaction consisting of a coupled all-trans-retinyl ester hydrolysis and alkene geometric isomerization to produce 11-cis-retinol. Early work on this isomerohydrolase...
Paper Details
Title
Retinal pigment epithelium 65 kDa protein (RPE65): An update
Published Date
May 1, 2022
Volume
88
Pages
101013 - 101013
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