Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer
Abstract
Basal/squamous (Ba/Sq) subtype represents an intrinsic and robust group in the consensus molecular classification of muscle-invasive bladder cancer (MIBC), with poor outcome and controversial chemosensitivity. We aimed to investigate the spectrum of intratumor heterogeneity (ITH) in the Ba/Sq subtype. First, we validated a 29-gene NanoString CodeSet to predict the Ba/Sq subtype for FFPE samples. We identified heterogeneous Ba/Sq tumors in a...
Paper Details
Title
Multilayer spectrum of intratumoral heterogeneity in basal bladder cancer
Published Date
Nov 9, 2021
Journal
Volume
256
Issue
1
Pages
108 - 118
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