Addressing Posttreatment Selection Bias in Comparative Effectiveness Research, Using Real-World Data and Simulation
Abstract
To examine methodologies that address imbalanced treatment switching and censoring, 6 different analytical approaches were evaluated under a comparative effectiveness framework: intention-to-treat, as-treated, intention-to-treat with censor-weighting, as-treated with censor-weighting, time-varying exposure, and time-varying exposure with censor-weighting. Marginal structural models were employed to address time-varying exposure, confounding, and...
Paper Details
Title
Addressing Posttreatment Selection Bias in Comparative Effectiveness Research, Using Real-World Data and Simulation
Published Date
Oct 6, 2021
Volume
191
Issue
2
Pages
331 - 340
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