A ketogenic diet protects DBA/1 and Scn1a mice against seizure-induced respiratory arrest independent of ketosis

Volume: 124, Pages: 108334 - 108334
Published: Nov 1, 2021
Abstract
Patients with uncontrolled epilepsy have a high risk of sudden unexpected death in epilepsy (SUDEP). Seizure-induced respiratory arrest (S-IRA) is thought to be the determining cause of death in many cases of SUDEP. The goal of the present study was to use Scn1aR1407X/+ (Dravet Syndrome, DS) and DBA/1 mice to determine: (1) the effect of a ketogenic diet (KD) on S-IRA and (2) the relationship between serum ketones and the protective effect of a...
Paper Details
Title
A ketogenic diet protects DBA/1 and Scn1a mice against seizure-induced respiratory arrest independent of ketosis
Published Date
Nov 1, 2021
Volume
124
Pages
108334 - 108334
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