Functional differences between Hsp105/110 family proteins in cell proliferation, cell division, and drug sensitivity

Volume: 122, Issue: 12, Pages: 1958 - 1967
Published: Oct 7, 2021
Abstract
The mammalian HSP105/110 family consists of four members, including Hsp105 and Apg-1, which function as molecular chaperones. Recently, we reported that Hsp105 knockdown increases sensitivity to the DNA-damaging agent Adriamycin but decreases sensitivity to the microtubule-targeting agent paclitaxel. However, whether the other Hsp105/110 family proteins have the same functional property is unknown. Here, we show that Apg-1 has different roles...
Paper Details
Title
Functional differences between Hsp105/110 family proteins in cell proliferation, cell division, and drug sensitivity
Published Date
Oct 7, 2021
Volume
122
Issue
12
Pages
1958 - 1967
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