Trends in regional morphological changes in the brain after the resolution of hypercortisolism in Cushing’s disease: a complex phenomenon, not mere partial reversibility

The adverse effects of hypercortisolism on the human brain have been highlighted in previous studies of Cushing's disease (CD). However, the relative alterations in regional hypercortisolism in the brain remain unclear. Thus, we investigated regional volumetric alterations in CD patients. We also analyzed the associations between these volumetric changes and clinical characteristics. The study participants comprised of active CD (n = 60),...