Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence

Volume: 17, Issue: 10, Pages: e1009969 - e1009969
Published: Oct 6, 2021
Abstract
The pathology associated with malaria infection is largely due to the ability of infected human RBCs to adhere to a number of receptors on endothelial cells within tissues and organs. This phenomenon is driven by the export of parasite-encoded proteins to the host cell, the exact function of many of which is still unknown. Here we inactivate the function of one of these exported proteins, PFA66, a member of the J-domain protein family. Although...
Paper Details
Title
Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence
Published Date
Oct 6, 2021
Volume
17
Issue
10
Pages
e1009969 - e1009969
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