Preparation of a heparin-like functionalized tannic acid-coated polyethersulfone ultrafiltration membrane for hemodialysis by a simple surface modification method

It is of practical significance to develop a heparin-free hemodialysis membrane that can be used for clinical applications in a simple way. In this work, a heparin-like coating loaded with SO3− and COOH was formed on a polyethersulfone (PES) ultrafiltration membrane by the hydrophobic interactions and hydrogen bonding of tannic acid (TA) with the PES membrane, the cross-linking of D-asparagine (DAS) with TA, and a Michael addition reaction of...