Clinically Translatable Approaches of Inhibiting TGF-β to Target Cancer Stem Cells in TNBC
Abstract
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that disproportionally accounts for the majority of breast cancer-related deaths due to the lack of specific targets for effective treatments. In this review, we highlight the complexity of the transforming growth factor-beta family (TGF-β) pathway and discuss how the dysregulation of the TGF-β pathway promotes oncogenic attributes in TNBC, which negatively affects patient...
Paper Details
Title
Clinically Translatable Approaches of Inhibiting TGF-β to Target Cancer Stem Cells in TNBC
Published Date
Oct 4, 2021
Journal
Volume
9
Issue
10
Pages
1386 - 1386
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